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Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo

The present study examined the heme oxygenase (HO) system in an in vivo murine model of pathological shear stress induced by partial carotid artery ligation. In this model, along with upregulation of vasculopathic genes, HO-1 is induced in the endothelium and adventitia, whereas HO-2 is mainly upreg...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Kang, Lu, Hillestad, Matthew L., Grande, Joseph P., Croatt, Anthony J., Barry, Michael A., Farrugia, Gianrico, Katusic, Zvonimir S., Nath, Karl A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451305/
https://ncbi.nlm.nih.gov/pubmed/25820397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00882.2014
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