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Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo

The present study examined the heme oxygenase (HO) system in an in vivo murine model of pathological shear stress induced by partial carotid artery ligation. In this model, along with upregulation of vasculopathic genes, HO-1 is induced in the endothelium and adventitia, whereas HO-2 is mainly upreg...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Kang, Lu, Hillestad, Matthew L., Grande, Joseph P., Croatt, Anthony J., Barry, Michael A., Farrugia, Gianrico, Katusic, Zvonimir S., Nath, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451305/
https://ncbi.nlm.nih.gov/pubmed/25820397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00882.2014
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