A carregar...

Opioids and Efflux Transporters. 1. P-Glycoprotein Substrate Activity of N-Substituted Analogs of Meperidine.

P-Glycoprotein (P-gp) is an efflux transporter which is up-regulated at the blood brain barrier in both morphine and oxycodone tolerant rats. Numerous studies have shown that many clinically employed opioid analgesics are substrates for P-gp, suggesting that up-regulation of P-gp may contribute to t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mercer, Susan L., Cunningham, Christopher W., Hassan, Hazem, Eddington, Natalie D., Coop, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850229/
https://ncbi.nlm.nih.gov/pubmed/17251015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.12.042
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!