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Gelatinase B (MMP-9) Is Not Essential in the Normal Kidney and Does Not Influence Progression of Renal Disease in a Mouse Model of Alport Syndrome

Matrix metalloproteinases are matrix degrading enzymes implicated in many biological processes, including development and inflammation. Gelatinase B (gelB; also known as MMP-9) is expressed in the kidney and is hypothesized to be involved in basement membrane remodeling and in preventing pathogenic...

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Autori principali: Andrews, Kaya L., Betsuyaku, Tomoko, Rogers, Sharon, Shipley, J. Michael, Senior, Robert M., Miner, Jeffrey H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850218/
https://ncbi.nlm.nih.gov/pubmed/10880400
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