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Loss of Heterozygosity in Fibrocystic Change of the Breast : Genetic Relationship Between Benign Proliferative Lesions and Associated Carcinomas

Loss of heterozygosity (LOH), a genetic change frequently detected in cancer, can also occur in benign epithelial foci in the breast. To characterize LOH in benign breast tissue, 32 cases containing the various components of fibrocystic change in the absence of malignancy were studied. Microdissecte...

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Detalhes bibliográficos
Main Authors: Washington, Constance, Dalbègue, Fabienne, Abreo, Fleurette, Taubenberger, Jeffery K., Lichy, Jack H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850200/
https://ncbi.nlm.nih.gov/pubmed/10880402
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