High-Resolution Chromosome 3p Allelotyping of Breast Carcinomas and Precursor Lesions Demonstrates Frequent Loss of Heterozygosity and a Discontinuous Pattern of Allele Loss

We performed high-resolution allelotyping for loss of heterozygosity (LOH) analysis on microdissected samples from 45 primary breast cancers, 47 mammary preneoplastic epithelial foci, and 18 breast cancer cell lines, using a panel of 27 polymorphic chromosome 3p markers. Allele loss in some regions...

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Hauptverfasser: Maitra, Anirban, Wistuba, Ignacio I., Washington, Constance, Virmani, Arvind K., Ashfaq, Raheela, Milchgrub, Sara, Gazdar, Adi F., Minna, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850416/
https://ncbi.nlm.nih.gov/pubmed/11438460
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