Disruption of Redox Homeostasis in Tumor Necrosis Factor-Induced Apoptosis in a Murine Hepatocyte Cell Line

Tumor necrosis factor (TNF) is a mediator of the acute phase response in the liver and can initiate proliferation and cause cell death in hepatocytes. We investigated the mechanisms by which TNF causes apoptosis in hepatocytes focusing on the role of oxidative stress, antioxidant defenses, and mitoc...

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Hauptverfasser: Pierce, Robert H., Campbell, Jean S., Stephenson, Alyssa B., Franklin, Christopher C., Chaisson, Michelle, Poot, Martin, Kavanagh, Terrance J., Rabinovitch, Peter S., Fausto, Nelson
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850198/
https://ncbi.nlm.nih.gov/pubmed/10880392
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