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Reduced alcohol consumption in mice lacking preprodynorphin.

Many studies suggest a role for endogenous opioid peptides and their receptors in regulation of ethanol intake. It is commonly accepted that the κ-opioid receptors and their endogenous ligands, dynorphins, produce a dysphoric state and therefore may be responsible for avoidance of alcohol. We used m...

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Detalhes bibliográficos
Main Authors: Blednov, Yuri A., Walker, Danielle, Martinez, Marni, Harris., R. Adron
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850187/
https://ncbi.nlm.nih.gov/pubmed/17307643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2006.12.002
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