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Deletion of Tlr3 reduces acute tolerance to alcohol and alcohol consumption in the intermittent access procedure in male mice

Pharmacological studies implicate toll-like receptor 3 (TLR3) signaling in alcohol drinking. We examined the role of TLR3 in behavioral responses to alcohol and GABAergic drugs by studying Tlr3 (−/−) mice. Because of opposing signaling between TLR3 and MyD88 pathways, we also evaluated Myd88 (−/−) m...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Blednov, Yuri A., Da Costa, Adriana, Mayfield, Jody, Harris, R. Adron, Messing, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772253/
https://ncbi.nlm.nih.gov/pubmed/32604471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12932
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