Increased Expression and Activation of Stress-Activated Protein Kinases/c-Jun NH(2)-Terminal Protein Kinases in Atherosclerotic Lesions Coincide with p53

Hyperlipidemia alters gene expression of arterial endothelial and smooth muscle cells (SMCs) and induces atherosclerotic lesions, in which cell proliferation and apoptosis co-exist. The signal transduction pathways that mediate these responses in the vessel wall in vivo have yet to be identified. St...

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Autores principales: Metzler, Bernhard, Hu, Yanhua, Dietrich, Hermann, Xu, Qingbo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2000
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850074/
https://ncbi.nlm.nih.gov/pubmed/10854211
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