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An amino acid outside the pore region influences apamin sensitivity in small conductance Ca(2+)-activated K(+) channels
Small conductance calcium-activated potassium channels (SK, K(Ca)) are a family of voltage-independent K(+) channels with a distinct physiology and pharmacology. The bee venom toxin apamin inhibits exclusively the three cloned SK channel subtypes (SK1, SK2 and SK3) with different affinity, highest f...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1849974/ https://ncbi.nlm.nih.gov/pubmed/17142458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607213200 |
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