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An amino acid outside the pore region influences apamin sensitivity in small conductance Ca(2+)-activated K(+) channels

Small conductance calcium-activated potassium channels (SK, K(Ca)) are a family of voltage-independent K(+) channels with a distinct physiology and pharmacology. The bee venom toxin apamin inhibits exclusively the three cloned SK channel subtypes (SK1, SK2 and SK3) with different affinity, highest f...

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Bibliografski detalji
Glavni autori: Nolting, Andreas, Ferraro, Teresa, D'hoedt, Dieter, Stocker, Martin
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1849974/
https://ncbi.nlm.nih.gov/pubmed/17142458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607213200
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