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FRAXA and FRAXE: Evidence against segregation distortion and for an effect of intermediate alleles on learning disability

There have been several claims of segregation distortion (meiotic drive) for loci associated with diseases caused by trinucleotide repeats, leading us to test for this phenomenon in a large study of the X-linked loci FRAXA and FRAXE. We found no evidence of meiotic drive in females and no convincing...

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Detalhes bibliográficos
Main Authors: Teague, J. W., Morton, N. E., Dennis, N. R., Curtis, G., McKechnie, N., Macpherson, J. N., Murray, A., Pound, M. C., Sharrock, A. J., Youings, S. A., Jacobs, P. A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18487/
https://ncbi.nlm.nih.gov/pubmed/9435259
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