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Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine.

The antiherpetic effects of a novel purine acyclic nucleoside, 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG), were compared with those of acyclovir in cell cultures and in mice. The modes of action of DHPG and acyclovir were similar in that herpes thymidine kinase phosphorylated each compound, and...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Antimicrob Agents Chemother
Główni autorzy: Smee, D F, Martin, J C, Verheyden, J P, Matthews, T R
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology (ASM) 1983
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6307132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.5.676
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