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Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with alpha-interferon against herpes simplex virus type 2 in mice.

The acyclic nucleoside DHPG [9-(1,3-dihydroxy-2-propoxymethyl)guanine] and recombinant human alpha-interferon of clones A/D potentiate each other's antiviral activity against a systemic infection with herpes simplex virus type 2. The effective dose at which 50% of the mice survived was lowered...

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Autores principales: Fraser-Smith, E B, Eppstein, D A, Marsh, Y V, Matthews, T R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1984
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC180056/
https://ncbi.nlm.nih.gov/pubmed/6335382
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