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Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine.

The antiherpetic effects of a novel purine acyclic nucleoside, 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG), were compared with those of acyclovir in cell cultures and in mice. The modes of action of DHPG and acyclovir were similar in that herpes thymidine kinase phosphorylated each compound, and...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Smee, D F, Martin, J C, Verheyden, J P, Matthews, T R
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1983
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6307132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.5.676
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