9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication.
A new compound, 9-(3,4-dihydroxybutyl)guanine, has been synthesized and its antiherpes activity determined. 9-(3,4-Dihydroxybutyl)guanine was selectively phosphorylated by herpes simplex virus thymidine kinase and had a high affinity for this enzyme, with an inhibition constant of 1.5 microM. In cel...
محفوظ في:
| الحاوية / القاعدة: | Antimicrob Agents Chemother |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1983
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184784/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6307131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.5.664 |
| الوسوم: |
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