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Structural investigation of the GlmS ribozyme bound to its catalytic cofactor

The GlmS riboswitch is located in the 5′-untranslated region of the gene encoding glucosamine-6-phosphate (GlcN6P) synthetase. The GlmS riboswitch is a ribozyme with activity triggered by binding of the metabolite GlcN6P. Presented here is the first structure of the GlmS ribozyme (2.5Å resolution) w...

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Détails bibliographiques
Auteurs principaux: Cochrane, Jesse C., Lipchock, Sarah V., Strobel, Scott A.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847778/
https://ncbi.nlm.nih.gov/pubmed/17196404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2006.12.005
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