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Towards Complete Sets of Farnesylated and Geranylgeranylated Proteins
Three different prenyltransferases attach isoprenyl anchors to C-terminal motifs in substrate proteins. These lipid anchors serve for membrane attachment or protein–protein interactions in many pathways. Although well-tolerated selective prenyltransferase inhibitors are clinically available, their m...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847700/ https://ncbi.nlm.nih.gov/pubmed/17411337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030066 |
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