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Single‐residue posttranslational modification sites at the N‐terminus, C‐terminus or in‐between: To be or not to be exposed for enzyme access

Many protein posttranslational modifications (PTMs) are the result of an enzymatic reaction. The modifying enzyme has to recognize the substrate protein's sequence motif containing the residue(s) to be modified; thus, the enzyme's catalytic cleft engulfs these residue(s) and the respective...

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Bibliografske podrobnosti
izdano v:Proteomics
Main Authors: Sirota, Fernanda L., Maurer‐Stroh, Sebastian, Eisenhaber, Birgit, Eisenhaber, Frank
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745020/
https://ncbi.nlm.nih.gov/pubmed/26038108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400633
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