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CTG Trinucleotide Repeat “Big Jumps”: Large Expansions, Small Mice
Trinucleotide repeat expansions are the genetic cause of numerous human diseases, including fragile X mental retardation, Huntington disease, and myotonic dystrophy type 1. Disease severity and age of onset are critically linked to expansion size. Previous mouse models of repeat instability have not...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847694/ https://ncbi.nlm.nih.gov/pubmed/17411343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030052 |
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