Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes

ARHGAP21 is a Rho family GTPase-activating protein (RhoGAP) that controls the Arp2/3 complex and F-actin dynamics at the Golgi complex by regulating the activity of the small GTPase Cdc42. ARHGAP21 is recruited to the Golgi by binding to another small GTPase, ARF1. Here, we present the crystal struc...

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Bibliografiska uppgifter
Huvudupphovsmän: Ménétrey, Julie, Perderiset, Mylène, Cicolari, Jérome, Dubois, Thierry, Elkhatib, Nadia, Khadali, Fatima El, Franco, Michel, Chavrier, Philippe, Houdusse, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847662/
https://ncbi.nlm.nih.gov/pubmed/17347647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601634
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