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Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes
ARHGAP21 is a Rho family GTPase-activating protein (RhoGAP) that controls the Arp2/3 complex and F-actin dynamics at the Golgi complex by regulating the activity of the small GTPase Cdc42. ARHGAP21 is recruited to the Golgi by binding to another small GTPase, ARF1. Here, we present the crystal struc...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847662/ https://ncbi.nlm.nih.gov/pubmed/17347647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601634 |
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