Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes

ARHGAP21 is a Rho family GTPase-activating protein (RhoGAP) that controls the Arp2/3 complex and F-actin dynamics at the Golgi complex by regulating the activity of the small GTPase Cdc42. ARHGAP21 is recruited to the Golgi by binding to another small GTPase, ARF1. Here, we present the crystal struc...

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Bibliographische Detailangaben
Hauptverfasser: Ménétrey, Julie, Perderiset, Mylène, Cicolari, Jérome, Dubois, Thierry, Elkhatib, Nadia, Khadali, Fatima El, Franco, Michel, Chavrier, Philippe, Houdusse, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847662/
https://ncbi.nlm.nih.gov/pubmed/17347647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601634
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