Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage

AMP-activated protein kinase (AMPK) responds to impaired cellular energy status by stimulating substrate metabolism for ATP generation. Mutation of the γ2 regulatory subunit of AMPK in humans renders the kinase insensitive to energy status and causes glycogen storage cardiomyopathy via unknown mecha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Luptak, Ivan, Shen, Mei, He, Huamei, Hirshman, Michael F., Musi, Nicolas, Goodyear, Laurie J., Yan, Jie, Wakimoto, Hiroko, Morita, Hiroyuki, Arad, Michael, Seidman, Christine E., Seidman, J.G., Ingwall, Joanne S., Balschi, James A., Tian, Rong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2007
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847536/
https://ncbi.nlm.nih.gov/pubmed/17431505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30658
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