TYROSINE 311 IS PHOSPHORYLATED BY c-Abl AND PROMOTES THE APOPTOTIC EFFECT OF PKCδ IN GLIOMA CELLS

In this study, we characterized the phosphorylation of tyrosine 311 and its role in the apoptotic function of PKCδ in glioma cells. We found that c-Abl phosphorylated PKCδ on tyrosine 311 in response to H(2)O(2) and that this phosphorylation contributed to the apoptotic effect of H(2)O(2). In contra...

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Main Authors: Lu, Wei, Finnis, Susan, Xiang, Cunli, Lee, Hae Kyung, Markowitz, Yael, Okhrimenko, Hana, Brodie, Chaya
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847386/
https://ncbi.nlm.nih.gov/pubmed/17126298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.11.028
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