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Relationship between antifungal activity and inhibition of sterol biosynthesis in miconazole, clotrimazole, and 15-azasterol.

The availability of Saccharomyces cerevisiae mutants which are defective in sterol biosynthesis makes it possible to determine whether the ability of several antifungal agents to inhibit cell growth is due to their effect on sterol production. 15-Aza-24-methylene-8,14-cholestadien-3 beta-ol (15-azas...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Taylor, F R, Rodriguez, R J, Parks, L W
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6344784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.4.515
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