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Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro comparative studies.

Aminoglycoside antibiotics induce an early and characteristic lysosomal phospholipidosis in cultured fibroblasts and in kidney tubular cells. We have recently demonstrated an inhibition of lysosomal phospholipases A1 and A2 by gentamicin and amikacin in vitro. In vivo, gentamicin decreases the activ...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Principais autores: Carlier, M B, Laurent, G, Claes, P J, Vanderhaeghe, H J, Tulkens, P M
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1983
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184667/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6847172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.3.440
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