Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro comparative studies.

Aminoglycoside antibiotics induce an early and characteristic lysosomal phospholipidosis in cultured fibroblasts and in kidney tubular cells. We have recently demonstrated an inhibition of lysosomal phospholipases A1 and A2 by gentamicin and amikacin in vitro. In vivo, gentamicin decreases the activ...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Carlier, M B, Laurent, G, Claes, P J, Vanderhaeghe, H J, Tulkens, P M
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1983
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6847172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.3.440
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