DNA-dependent protein kinase: DNA binding and activation in the absence of Ku
In mammalian cells, double-strand break repair and V(D)J recombination require DNA-dependent protein kinase (DNA-PK), a serine/threonine kinase that is activated by DNA. DNA-PK consists of a 460-kDa subunit (p460) that contains a putative kinase domain and a heterodimeric subunit (Ku) that binds to...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9435225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.2.525 |
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