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Neurogenin 3 Recruits CBP Co-activator to Facilitate Histone H3/H4 Acetylation in the Target Gene INSM1
INSM1 is a downstream target gene of ngn3. A promoter construct containing the −426/+40bp region transiently co-transfected into NIH-3T3 cells with a ngn3 expression plasmid resulted in a 12 fold increase in promoter activity. The ngn3/E47 heterodimer selectively binds and activates the E-box3 of th...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1839826/ https://ncbi.nlm.nih.gov/pubmed/17300785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.01.087 |
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