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Conserved aspartic acid 233 and alanine 231 are not required for poliovirus polymerase function in replicons

Nucleic acid polymerases have similar structures and motifs. The function of an aspartic acid (conserved in all classes of nucleic acid polymerases) in motif A remains poorly understood in RNA-dependent RNA polymerases. We mutated this residue to alanine in a poliovirus replicon. The resulting mutan...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Freistadt, Marion S, Eberle, Karen E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839082/
https://ncbi.nlm.nih.gov/pubmed/17352827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-28
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