Nerve Growth Factor-mediated Neurite Outgrowth via Regulation of Rab5

Nerve growth factor (NGF) induces neurite outgrowth and differentiation in a process that involves NGF binding to its receptor TrkA and endocytosis of the NGF–TrkA complex into signaling endosomes. Here, we find that biogenesis of signaling endosomes requires inactivation of Rab5 to block early endo...

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Main Authors: Liu, Jay, Lamb, Darija, Chou, Margaret M., Liu, Yong-Jian, Li, Guangpu
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2007
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838971/
https://ncbi.nlm.nih.gov/pubmed/17267689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0725
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