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Nerve Growth Factor-mediated Neurite Outgrowth via Regulation of Rab5

Nerve growth factor (NGF) induces neurite outgrowth and differentiation in a process that involves NGF binding to its receptor TrkA and endocytosis of the NGF–TrkA complex into signaling endosomes. Here, we find that biogenesis of signaling endosomes requires inactivation of Rab5 to block early endo...

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Main Authors: Liu, Jay, Lamb, Darija, Chou, Margaret M., Liu, Yong-Jian, Li, Guangpu
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838971/
https://ncbi.nlm.nih.gov/pubmed/17267689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0725
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