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Mst3b, a purine-sensitive Ste20-like protein kinase, regulates axon outgrowth
The growth of axons is fundamental to the development and repair of brain circuitry. We show here that Mst3b, a neuron-specific homolog of the yeast kinase Ste20, is critical for axon outgrowth. Mst3b is activated in response to trophic factors, and suppressing its expression (via siRNAs) or its fun...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
National Academy of Sciences
2006
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838749/ https://ncbi.nlm.nih.gov/pubmed/17114295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605135103 |
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