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Mst3b, a purine-sensitive Ste20-like protein kinase, regulates axon outgrowth

The growth of axons is fundamental to the development and repair of brain circuitry. We show here that Mst3b, a neuron-specific homolog of the yeast kinase Ste20, is critical for axon outgrowth. Mst3b is activated in response to trophic factors, and suppressing its expression (via siRNAs) or its fun...

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Bibliografiska uppgifter
Huvudupphovsmän: Irwin, N., Li, Y.-M., O'Toole, J. E., Benowitz, L. I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838749/
https://ncbi.nlm.nih.gov/pubmed/17114295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605135103
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