Alanine–glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer

Mutations in the alanine–glyoxylate amino transferase gene (AGXT) are responsible for primary hyperoxaluria type I, a rare disease characterized by excessive hepatic oxalate production that leads to renal failure. We generated a null mutant mouse by targeted mutagenesis of the homologous gene, Agxt,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Salido, Eduardo C., Li, Xiao M., Lu, Yang, Wang, Xia, Santana, Alfredo, Roy-Chowdhury, Namita, Torres, Armando, Shapiro, Larry J., Roy-Chowdhury, Jayanta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838738/
https://ncbi.nlm.nih.gov/pubmed/17110443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607218103
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