In Vivo and in Vitro Examination of Stability of Primary Hyperoxaluria-associated Human Alanine:Glyoxylate Aminotransferase

Primary hyperoxaluria type I is a severe kidney stone disease caused by mutations in the protein alanine:glyoxylate aminotransferase (AGT). Many patients have mutations in AGT that are not deleterious alone but act synergistically with a common minor allele polymorphic variant to impair protein fold...

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Bibliographic Details
Main Authors:	Hopper, Erin D., Pittman, Adrianne M. C., Fitzgerald, Michael C., Tucker, Chandra L.
Format:	Artigo
Language:	Inglês
Published:	American Society for Biochemistry and Molecular Biology 2008
Subjects:	Protein Structure and Folding
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2576547/ https://ncbi.nlm.nih.gov/pubmed/18782763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803525200
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In Vivo and in Vitro Examination of Stability of Primary Hyperoxaluria-associated Human Alanine:Glyoxylate Aminotransferase

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