Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay

De novo methylation of CpG islands is a common phenomenon in human cancer, but the mechanisms of cancer-associated DNA methylation are not known. We have used tiling arrays in combination with the methylated CpG island recovery assay to investigate methylation of CpG islands genome-wide and at high...

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Bibliografiske detaljer
Main Authors: Rauch, Tibor, Wang, Zunde, Zhang, Xinmin, Zhong, Xueyan, Wu, Xiwei, Lau, Sean K., Kernstine, Kemp H., Riggs, Arthur D., Pfeifer, Gerd P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838508/
https://ncbi.nlm.nih.gov/pubmed/17369352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701059104
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