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Correlation between mechanical strength of messenger RNA pseudoknots and ribosomal frameshifting

Programmed ribosomal frameshifting is often used by viral pathogens including HIV. Slippery sequences present in some mRNAs cause the ribosome to shift reading frame. The resulting protein is thus encoded by one reading frame upstream from the slippery sequence and by another reading frame downstrea...

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Autori principali: Hansen, Thomas M., Reihani, S. Nader S., Oddershede, Lene B., Sørensen, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838403/
https://ncbi.nlm.nih.gov/pubmed/17389398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608668104
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