Triplex structures in an RNA pseudoknot enhance mechanical stability and increase efficiency of –1 ribosomal frameshifting

Many viruses use programmed –1 ribosomal frameshifting to express defined ratios of structural and enzymatic proteins. Pseudoknot structures in messenger RNAs stimulate frameshifting in upstream slippery sequences. The detailed molecular determinants of pseudoknot mechanical stability and frameshift...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Chang, Kung-Yao, Chou, Ming-Yuan, Bustamante, Carlos, Tinoco, Ignacio
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722267/
https://ncbi.nlm.nih.gov/pubmed/19628688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905046106
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