Conversion of amoscanate to a mutagenic metabolite in gnotobiotic mice implanted with Streptococcus equinus.

Recent in vitro studies indicate that intestinal bacteria convert amoscanate (4-nitro-4'-isothiocyanodiphenylamine), an antischistosomal drug, to a potent mutagen. The present study indicates that the implantation of germfree mice with Streptococcus equinus, isolated from the small intestine of conv...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Reddy, B S, Batzinger, R P, Molineaux, C J, Bueding, E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1982
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7181482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.4.707
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