Conversion of amoscanate to a mutagenic metabolite in gnotobiotic mice implanted with Streptococcus equinus.

Recent in vitro studies indicate that intestinal bacteria convert amoscanate (4-nitro-4'-isothiocyanodiphenylamine), an antischistosomal drug, to a potent mutagen. The present study indicates that the implantation of germfree mice with Streptococcus equinus, isolated from the small intestine of conv...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Reddy, B S, Batzinger, R P, Molineaux, C J, Bueding, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7181482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.4.707
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