Low copy repeats mediate distal chromosome 22q11.2 deletions: Sequence analysis predicts breakpoint mechanisms

Genomic disorders contribute significantly to genetic disease and, as detection methods improve, greater numbers are being defined. Paralogous low copy repeats (LCRs) mediate many of the chromosomal rearrangements that underlie these disorders, predisposing chromosomes to recombination errors. Delet...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Shaikh, Tamim H., O’Connor, Ronald J., Pierpont, Mary Ella, McGrath, James, Hacker, April M., Nimmakayalu, Manjunath, Geiger, Elizabeth, Emanuel, Beverly S., Saitta, Sulagna C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2007
Témata:
Letter
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832095/
https://ncbi.nlm.nih.gov/pubmed/17351135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5986507
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky