Low copy repeats mediate distal chromosome 22q11.2 deletions: Sequence analysis predicts breakpoint mechanisms

Genomic disorders contribute significantly to genetic disease and, as detection methods improve, greater numbers are being defined. Paralogous low copy repeats (LCRs) mediate many of the chromosomal rearrangements that underlie these disorders, predisposing chromosomes to recombination errors. Delet...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Shaikh, Tamim H., O’Connor, Ronald J., Pierpont, Mary Ella, McGrath, James, Hacker, April M., Nimmakayalu, Manjunath, Geiger, Elizabeth, Emanuel, Beverly S., Saitta, Sulagna C.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2007
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832095/
https://ncbi.nlm.nih.gov/pubmed/17351135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5986507
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker