Loading...

Characterization of the structure, function, and mechanism of B2 RNA, an ncRNA repressor of RNA polymerase II transcription

We previously found that the SINE-encoded mouse B2 RNA binds RNA polymerase II and represses mRNA transcription during the cellular heat-shock response. In vitro B2 RNA assembles into preinitiation complexes on promoter DNA via its interaction with the polymerase, thus rendering the complexes inacti...

Full description

Saved in:
Bibliographic Details
Main Authors: Espinoza, Celso A., Goodrich, James A., Kugel, Jennifer F.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831867/
https://ncbi.nlm.nih.gov/pubmed/17307818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.310307
Tags: Add Tag
No Tags, Be the first to tag this record!