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Characterization of the structure, function, and mechanism of B2 RNA, an ncRNA repressor of RNA polymerase II transcription

We previously found that the SINE-encoded mouse B2 RNA binds RNA polymerase II and represses mRNA transcription during the cellular heat-shock response. In vitro B2 RNA assembles into preinitiation complexes on promoter DNA via its interaction with the polymerase, thus rendering the complexes inacti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Espinoza, Celso A., Goodrich, James A., Kugel, Jennifer F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831867/
https://ncbi.nlm.nih.gov/pubmed/17307818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.310307
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