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Global analysis of alternative splicing during T-cell activation

The role of alternative splicing (AS) in eliciting immune responses is poorly understood. We used quantitative AS microarray profiling to survey changes in AS during activation of Jurkat cells, a leukemia-derived T-cell line. Our results indicate that ∼10%–15% of the profiled alternative exons under...

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Bibliografske podrobnosti
Main Authors: Ip, Joanna Y., Tong, Alan, Pan, Qun, Topp, Justin D., Blencowe, Benjamin J., Lynch, Kristen W.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831861/
https://ncbi.nlm.nih.gov/pubmed/17307815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.457207
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