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Global analysis of alternative splicing during T-cell activation

The role of alternative splicing (AS) in eliciting immune responses is poorly understood. We used quantitative AS microarray profiling to survey changes in AS during activation of Jurkat cells, a leukemia-derived T-cell line. Our results indicate that ∼10%–15% of the profiled alternative exons under...

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Détails bibliographiques
Auteurs principaux: Ip, Joanna Y., Tong, Alan, Pan, Qun, Topp, Justin D., Blencowe, Benjamin J., Lynch, Kristen W.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831861/
https://ncbi.nlm.nih.gov/pubmed/17307815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.457207
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