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Global analysis of alternative splicing during T-cell activation

The role of alternative splicing (AS) in eliciting immune responses is poorly understood. We used quantitative AS microarray profiling to survey changes in AS during activation of Jurkat cells, a leukemia-derived T-cell line. Our results indicate that ∼10%–15% of the profiled alternative exons under...

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Detalhes bibliográficos
Main Authors: Ip, Joanna Y., Tong, Alan, Pan, Qun, Topp, Justin D., Blencowe, Benjamin J., Lynch, Kristen W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831861/
https://ncbi.nlm.nih.gov/pubmed/17307815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.457207
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