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Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin.

The importance of heparan sulfate proteoglycans (HSPGs) in neurodevelopment is becoming increasingly clear. However, studies on HSPGs are hampered by pleiotropic effects when synthesis or modification of heparan sulfate itself is targeted, and by redundancy when the core proteins are altered. Gain-o...

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Bibliografische gegevens
Hoofdauteurs: Fuerst, Peter G., Rauch, Steven M., Burgess, Robert W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831846/
https://ncbi.nlm.nih.gov/pubmed/17196957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.11.033
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