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Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin.
The importance of heparan sulfate proteoglycans (HSPGs) in neurodevelopment is becoming increasingly clear. However, studies on HSPGs are hampered by pleiotropic effects when synthesis or modification of heparan sulfate itself is targeted, and by redundancy when the core proteins are altered. Gain-o...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1831846/ https://ncbi.nlm.nih.gov/pubmed/17196957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.11.033 |
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