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Enzymatic and Cellular Study of a Serotonin N-Acetyltransferase Phosphopantetheine-based Prodrug
Serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) regulates the daily rhythm in the production of melatonin and is therefore an attractive target for pharmacologic modulation of the synthesis of this hormone. Previously prepared bisubstrate analogs show potent inhibition of A...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1831523/ https://ncbi.nlm.nih.gov/pubmed/17258461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.12.016 |
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