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The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function
BACKGROUND: Mutations in the PTEN induced putative kinase 1 (PINK1) are implicated in early-onset Parkinson's disease. PINK1 is expressed abundantly in mitochondria rich tissues, such as skeletal muscle, where it plays a critical role determining mitochondrial structural integrity in Drosophila...
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| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1831481/ https://ncbi.nlm.nih.gov/pubmed/17362513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-74 |
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